FACTORS FOR DE-SELECTION OF POTENTIAL CANDIDATES FOR LIVER DONOR LIVER TRANPLANT IN A TETIARY CARE HOSPITAL

Abstract

Objective: To look for factors responsible for de-selection of patients for live donor liver transplantat tertiary care hospital.

Study Design: Correlational study.

Place and Duration of Study: Study was conducted in Gastroenterology Department of Military Hospital from Nov 2017 to Nov 2018.

Methodology: A study was conducted on patients diagnosed with end stage liver disease (ESLD) and qualifying the criteria for liver transplant at our hospital by a consultant gastroenterologist on the basis of clinical findings, relevant investigations and Model for End Stage Liver Disease (MELD) score.

Results: Out of 145 patients included in the final analysis 69.6% were male and 30.4% were female. Eighty nine (61.3%) patients presented with the chronic liver disease secondary to the hepatitis C virus (HCV). Fifty patients were declared unfit due to some underlying conditions. Advanced stage of hepatocellular carcinoma in 10(20%) patients was the commonest factor leading for rejection of potential recipients for live donor liver transplant followed by spontaneous bacterial peritonitis in 9 (18%) patients.

Conclusion: This study gives a detailed account of the possible factors which could lead to the de-selection of potential candidates for live donor liver transplant. It becomes very important for a third world country like ours where resources are limited to screen the patients thoroughly before administering this highly invasive and expensive treatment so that whole of the effort does not get wasted on a patient who could not get adequate benefit from it due to other medical conditions.