@article{Haq_Sheikh_Ashfaq_Ahmed_Ahmed_2019, title={ROSUVASTATIN AS A POSSIBLE TREATMENT FOR SUDDEN SENSORINEURAL HEARING LOSS}, volume={69}, url={https://www.pafmj.org/PAFMJ/article/view/3630}, abstractNote={<p><strong>Objective:</strong> To determine the role of Rosuvastatin as a possible treatment of sudden sensorineural hearing loss.</p> <p><strong>Study Design:</strong> Quasi-experimental study.</p> <p><strong>Place and Duration of Study:</strong> ENT Departments, Combined Military Hospital Quetta & Combined Military Hospital Lahore, from Apr 2015 to Sep 2017.</p> <p><strong>Methodology:</strong> This quasi-experimental study performed at Combined Military Hospital Quetta & Combined Military Hospital Lahore comprised of seventy-eight patients of sudden sensorineural hearing loss (SSNHL) having hyperlipidemia. Patients pre-treatment total serum cholesterol was measured, and hearing loss in speech frequencies was recorded on audiometry. The seventy-eight patients were administered tablet Rosuvastatin 10mg once daily with low fat diet for 4 months. On completion of 4 months of treatment, patients were selected by using non probability purposive sampling and divided into responder and non-responder group depending on total serum cholesterol levels. Post treatment total serum cholesterol levels and improvement in hearing levels were also recorded and graded according to siegel’s criteria.</p> <p><strong>Results:</strong> Total serum cholesterol came to within normal limits in 43 (55.1%) patients (responder), while it remained high in 35 (44.9%) patients (non-responder group). Improvement in hearing scores was assessed using siegel’s criteria. pearson chi square test showed statistically significant improvement (p=0.001) in hearing scores among responder group as compared to non-responder group.</p> <p><strong>Conclusion:</strong> Sudden sensorineural hearing loss, in patients having hyperlipidemia, can be managed by treating hyperlipidemia with lipidlowering agent rosuvastatin.</p>}, number={6}, journal={Pakistan Armed Forces Medical Journal}, author={Haq, Nadeem Ul and Sheikh, Zeeshan Ayub and Ashfaq, Ahmed Hasan and Ahmed, Azeema and Ahmed, Naeema}, year={2019}, month={Dec.}, pages={1184–88} }