INTRAPERITONEAL INFILTRATION OF ROPIVACAINE FOR POST-OPERATIVE ANALGESIA IN OPEN CHOLECYSTECTOMY

Ropivacaine in Open Cholecystectomy

Abstract

Objective: To assess the role of Intraperitoneal infiltration of Ropivacaine for post-op analgesia in open
cholecystectomy in a low resource setting.
Study Design: Randomized controlled trial.
Place and Duration of Study: Study was conducted at department of Anesthesia, Scouts Hospital Chitral, from Jul 2014 to Jun 2016.
Material and Methods: After taking approval from hospital ethical committee, total 126 patients were divided randomly in two groups. Group I (study group) was given intraperitoneal ropivacaine and group II (control group) was given routine standard analgesia. After complete recovery, pain was measure on VAS score (1-10) at 1 hour, 6 hour and 24 hour in all patients. Patients having pain score of 4 or more were managed with nalbuphine 5 mg IV bolus. Data was analyzed by SPSS version 16.
Results: The comparison of pain score (after 1, 6and 24 hours of surgery), showed that study group had
significantly (p-value<0.05) less mean pain score as compared with placebo group. Significant rate of
nausea/vomiting was observed (p-value<0.05) higher (62%) in placebo group as compared with (38%) in study group. Statistically there was no significant difference (p-value>0.05) between groups on the basis of mean age (47.89 ± 8.56 vs. 48.75 ± 9.36), gender (Females 70% vs. 68%), duration of the surgery (88.54 ± 12.34 minutes vs. 91.70 ± 13.50 minutes) and American society of anesthesiologist (ASA) grades in study and placebo group patients respectively.
Conclusion: Intraperitoneal ropivacaine infiltration helped in reducing the post op pain significantly in open cholecystectomy.