HISTOLOGICAL CONSEQUENCES OF CONSUMPTION OF ENERGY DRINK ON RENAL TUBULES: Energy Drink and Renal Tubules

Ammara Rasheed; Imtiaz Aslam; Raafea Tafweez; Muhammad Rizwan Bashir Kiani; Muhammad Kamran Ameer; Arslan Akbar Saeed

doi:10.51253/pafmj.v71i5.6326

Authors

Ammara Rasheed Nishtar Medical University, Multan Pakistan
Imtiaz Aslam Fatima Jinnah Medical University, Lahore Pakistan
Raafea Tafweez King Edward Medical University, Lahore Pakistan
Muhammad Rizwan Bashir Kiani Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Kamran Ameer Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Arslan Akbar Saeed Nishtar Medical University, Multan Pakistan

DOI:

https://doi.org/10.51253/pafmj.v71i5.6326

Keywords:

Caffeine, Energy drink, Renal tubules, Renal vacuolization, Taurine

Abstract

Objective: To investigate the outcomes of energy drink on renal tubules of albino rats.

Study Design: Laboratory-based experimental study.

Place and Duration of Study: King Edward Medical University, Lahore from Aug 2018 to Dec 2019.

Methodology: Group A and B were experimental groups received 1.5ml/kg and 2.2ml/kg body weight of energy drink, respectively. Group C received 1ml/kg body weight of distilled water. Comparison among groups was made by applying One-Way ANOVA for quantitative variables. Tukey’ test was used for post hoc analysis. For qualitative variables, chi-square test was applied to make comparison among groups

Results: The mean initial and final weight of animals was around 152.7 ± 5.3g and 171.9 ± 5.1g, respectively. The mean paired kidney weight, relative tissue weight index, length and width of kidneys for all three groups were found insignificant. Microscopic examination showed tubular vacuolization in groups A and B showing p-value of 0.027.

Conclusion: Consumption of energy drinks results in histopathological injury of epithelial cells of renal tubules.