CYTOLOGICAL GRADING OF BREAST CANCER ACCORDING TO ROBINSON’S GRADING SYSTEM
Cytological Grading Of Breast Cance
Keywords:Anaplasia, Breast, Carcinoma, Chromatin, Ductal, Fine- Needle Aspiration, Pakistan
Objective: To see the correlation between cytological parameters and grading of breast cancer according to Robinson’s grading system on Fine needle aspiration smears. Study design: It was a correlational descriptive study.
Study Design: It was a corelational descriptive study.
Place and Duration of Study: It was conducted in the Histopathology Department, Army Medical College, National University of Sciences and Technology (NUST), Rawalpindi, Pakistan from Nov 2012 to Nov 2013.
Material and Methods: All cases diagnosed as breast cancer (C 5) or suspicious of breast cancer (C 4), on Fine needle aspiration cytology, were included in the study and women already taking treatment were excluded. A total of 102 samples were included in the study through non probability convenience sampling.
Result: The cytological parameters of Robinson’s grading system including cell dissociation, nuclear margins and nuclear chromatin showed weak correlation with tumor grade. While cell size, cell uniformity and nucleoli showed moderate correlation. All the parameters were statistically significant with p-value<0.05.
Conclusion: This study concludes that all the cytological parameters of Robinson’s grading system have correlation with tumor grade.