Seroprevalence of SARS-CoV2 Antibodies among Patients and Healthy Individuals of Lahore

Kanwal Hassan Cheema; Muhammad Saeed Anwar; Fatima Hameed; Majid Rauf; Afia Sarwar; Mariam Danish Iqbal

doi:10.51253/pafmj.v73i1.6823

Authors

Kanwal Hassan Cheema CMH Lahore Medical College, Lahore/National University of Medical Sciences (NUMS) Pakistan
Muhammad Saeed Anwar CMH Lahore Medical College, Lahore/National University of Medical Sciences (NUMS) Pakistan
Fatima Hameed CMH Lahore Medical College, Lahore/National University of Medical Sciences (NUMS) Pakistan
Majid Rauf Avicenna Medical College, Lahore Pakistan
Afia Sarwar CMH Lahore Medical College, Lahore/National University of Medical Sciences (NUMS) Pakistan
Mariam Danish Iqbal Indus Hospital, Lahore Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i1.6823

Keywords:

COVID-19 infection, SARS-CoV-2 antibodies, Seroprevalence

Abstract

Objective: To determine the seroprevalence of SARS-CoV2 antibodies in patients and healthy individuals presenting to a tertiary care hospital in Lahore.

Study Design: Cross-sectional study

Place and Duration of Study: Pathology Department of Surayya Azeem Hospital, Lahore Pakistan, from May to Jul 2020.

Methodology: The study included clinically suspected patients of COVID-19 referred by clinicians and healthy individuals presenting to the hospital for the SARS-CoV-2 antibody test, irrespective of age and gender.

Results: The SARS-CoV-2 antibody positivity was 704(59.4%) in our study. Out of 1184 individuals tested, 690 patients had a positive clinical history of COVID-19 infection, and 517(74.9%) were positive for COVID-19 antibodies. Out of 494 asymptomatic healthy individuals, positivity for COVID-19 antibodies was 187(37.8%). It was observed that positivity was significantly higher 169(44.0%) in contacts of COVID-19 infection patients compared to asymptomatic healthy individuals 18(16.3%).

Conclusion: Our study shows that the seroprevalence of SARS-CoV-2 antibodies in the general public in Pakistan has greatly increased.