Impact of Gluten on Irritable Bowel Syndrome

Authors

  • Sana Uruj Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Zafar Ali Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Natasha Sarwar Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Amina Hussain Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Waseem Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i4.6843

Keywords:

Gluten, Irritable bowel syndrome, Quality of life

Abstract

Objective: To assess the impact of a gluten-free diet on the quality of life of patients managed for irritable bowel syndrome at a tertiary care hospital

Study Design: Prospective comparative study.

Place and Duration of Study: Department of Medicine/Gastroenterology, Pak Emirates Military Hospital, Rawalpindi Pakistan from Jul 2020 to May 2021.

Methodology: Two hundred patients with irritable bowel syndrome and diagnosed on the basis of Rome-IV criteria were included in this study. They were divided into two groups via a lottery method. Group-1 received treatment as usual, depending upon the type of irritable bowel syndrome. Group-2 received treatment as usual and a gluten-free diet. Quality of life was assessed after one month using the World Health Organization Quality of Life-Brief scale.

Results: Out of 200 patients with irritable bowel syndrome included in the study, 93(46.5%) were male, while 107(53.5%) were female. 125(62.5%) had good quality of life after one month of treatment, while 75(37.5%) had lesser quality of life. Statistical analysis revealed that irritable use of a gluten-free diet had a statistically significant relationship (p-value<0.001) with good quality of life after one month of treatment in study participants.

Conclusion: After one month of treatment, good quality of life was found in many patients with irritable bowel syndrome. The use of a gluten-free diet in addition to treatment, as usual, was associated with good quality of life than routine treatment in these patients.

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Published

31-08-2023

Issue

Section

Original Articles

How to Cite

1.
Uruj S, Ali MZ, Sarwar N, Hussain A, Waseem M. Impact of Gluten on Irritable Bowel Syndrome. Pak Armed Forces Med J [Internet]. 2023 Aug. 31 [cited 2024 Jun. 15];73(4):1124-7. Available from: https://www.pafmj.org/PAFMJ/article/view/6843