Comparison of Efficacy of Warm Compresses Versus Loteprednol-Tobramycin Combination Therapy in the Management of Posterior Blepharitis

Authors

  • Maryam Nisar Department of Ophthalmology, Armed Forces Institute of Opthamology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Abid Hassan Naqvi Department of Ophthalmology, Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Nisar Ahmed Khan Department of Community Medicine, Abbottabad International Medical Institute, Abbottabad Pakistan
  • Muhammad Shahid Tarar Department of Ophthalmology, Armed Forces Institute of Opthamology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Nazia Iqbal Department of Ophthalmology, Armed Forces Institute of Opthamology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i4.7695

Keywords:

Blepharitis, Meibomian gland dysfunction, Warm compresses

Abstract

Objectives: to compare the efficacy of warm compresses to add-on therapy with Loteprednol-Tobramycin in patients withposterior Blepharitis.

Study Design: Quasi-experimental study.

Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi Pakistan, from Jun 2020 to Jul 2021.

Methodology: Pre-diagnosed posterior blepharitis patients using warm compresses (Group-A) and add-on antibiotic steroid therapy (Group-B) were included in the study. A detailed history and ophthalmic examination evaluated tear breakup time, tear film height, intra-ocular pressure measurement, meibomian gland function, structure, and meibum appearance. In addition, the patient's symptoms were noted through the ocular surface disease index questionnaire.

Results: The study sample had seventy-one males (56%) and 55 females (43.6%) with mean age of 35.33±12.24 years. The clinical parameters in the two groups were almost alike at enrollment. There was a significant improvement in the clinical parameters in both groups. With slightly better improvement among Group-B (using Loteprednol-Tobramycin), Only two individuals did not report an increase in IOP at six weeks of treatment in Group-B. (p=0.53).

Conclusion: Lid hygiene with warm compresses is an effective alternative with no side effects, provided if appropriately practised; however, add-on therapies may further improve MGD and Blepharitis.
Keywords: Blepharitis, Meibomian gland dysfunction, Warm compresses.

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Published

31-08-2023

How to Cite

1.
Nisar M, Naqvi AH, Khan NA, Tarar MS, Iqbal N. Comparison of Efficacy of Warm Compresses Versus Loteprednol-Tobramycin Combination Therapy in the Management of Posterior Blepharitis. Pak Armed Forces Med J [Internet]. 2023 Aug. 31 [cited 2024 May 20];73(4):1067-70. Available from: https://www.pafmj.org/PAFMJ/article/view/7695

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