Sol Brain, Pre-Operative Magnetic Resonance Spectroscopy and Surgical Biopsy Yield

Authors

  • Khurshid Ali Bangash Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Nasrin Yousaf Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Sohail Ilyas Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Rashid Mahmood Combined Military Hospital, Sialkot/National University of Medical Sciences (NUMS) Pakistan
  • Ishrat Parveen Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Ajmal Yousaf Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Arshad Khushdil Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Sharoon Nathaniel Combined Military Hospital, Quetta/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i2.9503

Keywords:

Brain, Histopathology, Magnetic resonance spectroscopy, Tumour

Abstract

Objective: To ascertain the positive predictive value (PPV) of magnetic resonance spectroscopy (MRS) in diagnosing neoplastic intracranial masses by taking histopathology as a benchmark.

Study Design: Cross-sectional study.

Place and Duration of Study: Combined Military Hospital, Rawalpindi Pakistan, from Jan 2019 to Jun 2021.

Methodology: After approval from the Ethical Review Committee, 64 patients with neoplastic intracranial mass lesions on MRI were incorporated into the study. Patients with a history of brain surgery done previously, breastfeeding females, claustrophobia, already diagnosed type of tumour, and contraindication to MRI were excluded. MR Spectroscopy was performed, and findings were correlated with histopathology.

Results: Of 64 patients, 39(60.94%) were males, and 25(39.06%) were females. Magnetic Resonance Spectroscopy (MRS) supported the diagnosis of neoplastic brain lesions in all 64 patients. Histopathology confirmed malignant brain lesions in 59 cases, whereas 05 cases had benign lesions. PPV of MRS in the diagnosis of neoplastic brain lesions was 92.19%.

Conclusion: This study concluded that MRS is a non-invasive option having a very good PPV in determining neoplastic brain lesions.

Downloads

Download data is not yet available.

Downloads

Published

04-05-2023

Issue

Section

Original Articles

How to Cite

1.
Bangash KA, Yousaf N, Ilyas S, Mahmood R, Parveen I, Yousaf A, et al. Sol Brain, Pre-Operative Magnetic Resonance Spectroscopy and Surgical Biopsy Yield. Pak Armed Forces Med J [Internet]. 2023 May 4 [cited 2024 Oct. 11];73(2):587-90. Available from: https://www.pafmj.org/PAFMJ/article/view/9503