Effects of Post-Operative Cognitive Dysfunction (Pocd) After General Anesthesia In Geriatric Patients

Najaf  Imtiaz; Abdul Hameed  Bhatti; Muhammed  Wasib; Saad  Hameed; Shais  Talat; Rana Faizan  Asghar

doi:10.51253/pafmj.v76iSUPPL-9.10017

Authors

Najaf Imtiaz Department of Anesthesia, Combined Military Hospital Dera Nawab Sahib/National University of Medical Sciences (NUMS) Pakistan
Abdul Hameed Bhatti Department of Anesthesia, PAF Hospital Islamabad
Muhammed Wasib Department of Anesthesia, Combined Military Hospital Nowshera /National University of Medical Sciences (NUMS) Pakistan
Saad Hameed Department of Anesthesia, Scouts hospital Chitral Pakistan
Shais Talat Department of Anesthesia, Combined Military Hospital Thall /National University of Medical Sciences (NUMS) Pakistan
Rana Faizan Asghar Department of Anesthesia, 1 Mtn Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-9.10017

Keywords:

General anesthesia, geriatric, post-operative cognitive dysfunction (POCD)

Abstract

Objective: To compare the effects of post-operative cognitive dysfunction (POCD) after general anesthesia in geriatric patients

Study Design: Prospective observational study

Place and Duration of Study: Anesthesia Department of Combined Military Hospital, Peshawar, Pakistan, from Jun to Dec 2022.

Methodology: A sample of 330 patients between the ages of 55 and 85 years was included in the study, undergoing elective surgery under general anesthesia. Primary variables measured were MMSE pre-operatively and 12 and 24 hours after surgery, and the effects of POCD were assessed.

Results: Mean age of patients was 69.52±6.69 years, and mean weight was 68.44±3.81 kg. Mean duration of surgeries done was 129.26±6.6 minutes. Gender distribution revealed a total of 148 (44.8%) males and 182 (55.2%) females in the group. When cognitive variables were checked in the patients, it was seen that there was marked deterioration in orientation, registration, attention, recall, language, and copying at the 12- and 24-hour intervals on the MMSE. The median MMSE score at the 12-hour interval was 26 (IQR=2.00) versus 27(IQR=1.00) at the 24-hour interval (p<0.001). The score improved at the 24-hour interval but was still lower than the score assessed pre-operatively.

Conclusion: It was concluded that general anesthesia is associated with POCD, predominantly affecting the logical memory in the geriatric population.

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