Comparison of Early Mortality and Morbidity of Off Pump vs On Pump Coronary Artery Bypass Graft Surgery in High-Risk Patients

Authors

  • Atif Nawaz Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Nasir Ali Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Sikandar Hayat Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Farah Sobia Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Ahsan Sajjad Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-3.10897

Keywords:

Cardiopulmonary Bypass (CPB), Coronary Artery Bypass Graft, Left Ventricular Dysfunction, Myocardial Infarction, Off Pump, On Pump.

Abstract

Objective: To compare the early mortality and morbidity of high-risk patients following off-pump and on-pump Coronary Artery Bypass Grafting (CABG).

Study Design: Analytical Cross-sectional study.

Place and Duration of Study: Tertiary Care Cardiac Center, Rawalpindi Pakistan, from Oct 2022 to Mar 2023.

Methodology: Two hundred and forty-three patients undergoing on-pump CABG(ONCAB) or off-pump CABG(OPCAB) with an Ejection Fraction (EF) of <35%, history of stroke, Glomerular Filtration Rate (GFR) <60 ml/min/1.73m2 or a serum creatinine level >1.5 mg/dl, and Chronic Obstructive Pulmonary Disease (COPD) were included using consecutive sampling. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 23:00. Descriptive statistics were used to calculate Mean±SD for continuous variables like (age, EF and duration of hospital stay). Frequencies and percentages were calculated for categorical variables like (gender and post-op outcomes). Chi-square & t-test were used to make comparison between both groups, p-value <0.05 was considered significant. Top of Form.

Results: Out of two hundred and forty-three (n=243) patients, 193(79.4%) males and 50(20.6%) females with mean age 49.04±7.75 years underwent ONCAB 150(61.9%) and OPCAB 93(38.1%). ONCAB had slightly higher rates of Myocardial Infarction (5.3%) and Stroke (6%) compared to OPCAB (1.1% for both), p-values of 0.08 and 0.06, respectively. Respiratory complications were more common in ONCAB, with 9.3% requiring re-intubation, compared to 2.2% in the OPCAB group (p=0.02). ONCAB also had a slightly longer hospital stay (7.1±1.4 days) compared to OPCAB (6.7±1.6 days) (p=0.03). Additionally, ONCAB had higher rates of re-.....

Conclusion: OPCAB showed lower rates of complications, indicates the...

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References

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Published

30-05-2025

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Original Articles

How to Cite

1.
Nawaz A, Ali N, Hayat S, Sobia F, Sajjad A. Comparison of Early Mortality and Morbidity of Off Pump vs On Pump Coronary Artery Bypass Graft Surgery in High-Risk Patients. Pak Armed Forces Med J [Internet]. 2025 May 30 [cited 2025 Aug. 24];75(SUPPL-3):S446-S450. Available from: https://www.pafmj.org/PAFMJ/article/view/10897