Role of Intravenous Cefuroxime Antibiotic Prophylaxis in the Prevention of Surgical Site Infection in Open Mesh Inguinal Hernia Repair
DOI:
https://doi.org/10.51253/pafmj.v73i6.11424Keywords:
Mesh inguinal hernia repair, Pre-operative cefuroxime administration, Surgical (SSI), Wound Infection (WI)Abstract
Objective: To compare pre-operative intravenous Cefuroxime prophylaxis to no prophylaxis regarding the development of
surgical site infection in inguinal hernia mesh repair.
Study Design: Quasi-experimental study.
Place and Duration of Study: Department of Surgery, Combined Military Hospital, Bahawalnager Pakistan, from Nov 2015
to Nov 2017.
Methodology: A total of 230 patients were included (115 patients in each group). Group-A patients were subjected to preoperative administration of 1.5 gm intravenous Cefuroxime 1 hour before surgery, while Group B patients were subjected to
no antibiotic prophylaxis following mesh repair. Development of post-operative surgical site infection (SSI) was checked till
the 30th post-operative day (POD).
Results: Post-operative surgical site infection was comparatively less in Group-A (3.4%) as compared to Group-B (10.4%),
which was statistically significant (p-value0.038).
Conclusion: Pre-operative intravenous Cefuroxime prophylaxis significantly reduces post-operative SSI following mesh
inguinal hernia repair.
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