A Comparative Study on the Efficacy of Platelet-Rich Fibrin vs. Standard Care in Reducing Pain and Swelling Post-Surgical Extraction of Impacted Mandibular Third Molars

Jazib pervez; Sobia  Manzoor; Taimur ul  Hassan; Rizwan Zafar  Langrial; Mujeeb  Ahmed; Memoona  Ali

doi:10.51253/pafmj.v76iSUPPL-5.12290

Authors

Jazib pervez Department of Operative Dentistry, Bakhtawar Amin Dental College & Hospital, Multan Pakistan
Sobia Manzoor Department of Oral & Maxillofacial Surgery, Bakhtawar Amin Dental College & Hospital, Multan Pakistan
Taimur ul Hassan Department of Oral & Maxillofacial Surgery, Bakhtawar Amin Dental College & Hospital, Multan Pakistan
Rizwan Zafar Langrial Department of Periodontology, Bakhtawar Amin Dental College & Hospital, Multan Pakistan
Mujeeb Ahmed Department of Oral & Maxillofacial Surgery, Bakhtawar Amin Dental College & Hospital, Multan Pakistan
Memoona Ali Department of Operative Dentistry, Bakhtawar Amin Dental College & Hospital, Multan Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-5.12290

Keywords:

Impaction, Platelet Rich Fibrin, Post-Operative Pain, Surgical Extraction, Swelling, Third Molars

Abstract

Objective: To compare outcomes of Application of platelet-rich fibrin versus standard care on pain and swelling in patients who are having surgical extraction of impacted mandibular 3rd molars.

Study Design: Randomized controlled trial (ACTRN: 0000387594).

Place and Duration of Study: Bakhtawar Amin Dental College & Hospital, Multan Pakistan, from Aug 2022 to Feb 2023.

Methodology: One hundred and sixty-eight patients included for surgical extraction of impacted third molar, were randomly assigned to Group A (platelet-rich fibrin) and Group B (standard care). In Group A, PRF was introduced in extraction sockets. On follow-up the outcomes in the form of pain and facial swelling were assessed on 3rd post-operative day.

Results: Mean age of patients in Group A was 34.45±9.04 years and Group B was 36.30±9.12 years with p-value of 0.187. There were 31(36.9%) males and 53(63.1%) females in Group A and 28(33.3%) males and 56(66.7%) females in Group B with insignificant p-value of 0.628. Mean facial swelling in Group A was 9.75±1.33mm and Group B was 11.19±1.48mm with p-value of <0.001. The Median pain score was 3 (IQR: 2) of all the patients included in this study. The median pain score of patients in Group A was (IQR: 2) and Group B was 4 (IQR: 1) with p-value of <0.001.

Conclusion: The application of PRF decrease postoperative pain and swelling after extraction of mandibular 3rd molars. Using PRF to fill a socket can be an effective way to reduce post-operative complications and is convenient to use in clinical practice.

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