Comparative Study of Topical Sucralfate and Normal Saline Dressing for Diabetic Ulcer-A Quasi-Experimental Study
DOI:
https://doi.org/10.51253/pafmj.v76i1.12445Keywords:
Diabetic foot, Dressings, Sucralfate, Saline solution, Wound healing.Abstract
Objective: To compare the effect of topical Sucralfate versus normal saline dressing in wound healing of diabetic ulcers.
Study Design: Quasi-experimental.
Place and Duration of Study: Department of Surgery, Combined Military Hospital, Multan Pakistan from Jan to Jun 2023.
Methodology: The study included 64 diabetic patients aged 25-75 years with long-standing diabetic grade 1 and 2 ulcers. Participants were distributed in 2 equal Groups by lottery method. Group-A patients were planned for topical Sucralfate dressings, whereas Group-B patients received normal saline dressings. The mean reduction in wound area and healing time were assessed and compared in both Groups.
Results: Out of 64 patients, 56 patients were included in the final analysis and eight were excluded due to death or complications. The mean age was 56.21±9.58 years in the topical Sucralfate Group and 57.70±12.01 years in the normal saline Group. The mean wound surface area was 185.24±22.01 cm2 in Group-A and 186.67±19.17 cm2 in Group-B (p=0.907). In weeks 1 and 3, the Sucralfate dressing Group showed more reduction in surface area, 12.31±2.23% and 72.69±9.54 %, respectively, whereas the normal saline Group had 10.59±2.56% and 47.44±6.99% reduction in wound size respectively (p<0.005). Healing time in the topical Sucralfate Group was less than in the normal saline Group, 26.38±2.63 days vs 36.96±3.79 days, respectively (p<0.005).
Conclusion: Topical Sucralfate dressings have been shown to be more successful and effective in treating diabetic ulcers than conventional normal saline dressings.
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Copyright (c) 2026 Sajjad Ahmad Ansari, Nadia Riaz , Dr Abdul Majid, Zain Farooq, Muhammad Waqas Ahmed Bhati, Afzal Saeed Awan
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