Hypopituitarism Presenting as Heart Failure-A Case Series

Authors

  • Imran Ahmad Department of Medicine, Akhtar Saeed Medical College, Rawalpindi Pakistan
  • Abdul Hameed Siddiqui Department of Adult Cardiology, Armed Forces Institute of Cardiology/ National Institute of Heart Diseases/National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Ahreema Siddiqui Department of Medicine, Akhtar Saeed Medical College, Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-3.12941

Keywords:

Cardiomyopathy, Cortisol, Empty Sella, Growth Hormone, Heart Failure, Hypopituitarism, Panhypopituitarism, Pituitary Gland.

Abstract

Hypopituitarism, an uncommon endocrine disorder, presents a diagnostic challenge due to its variable and often vague manifestations. It can have severe, life-threatening complications including heart failure. In this case series, we reported five cases with hypopituitarism presented as heart failure, each exhibited unique etiologies and presentations. Out of these, two cases were associated with Sheehan’s syndrome, two with Empty Sella Syndrome, and one with isolated ACTH deficiency. Clinical evaluation, hormonal assays, and imaging studies were instrumental in confirming diagnoses. Hormone replacement therapy led to symptomatic and functional cardiac recovery in these patients, highlighting the importance of considering hypopituitarism in cases of unexplained heart failure. This series emphasizes early recognition and appropriate treatment of hypopituitarism to prevent significant morbidity and mortality.

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References

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Published

30-05-2025

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Case Series

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How to Cite

1.
Ahmad I, Siddiqui AH, Siddiqui A. Hypopituitarism Presenting as Heart Failure-A Case Series. Pak Armed Forces Med J [Internet]. 2025 May 30 [cited 2025 Oct. 6];75(SUPPL-3):S488-S492. Available from: https://www.pafmj.org/PAFMJ/article/view/12941