Systemic Effects of Local Anesthesia on Hypertensive Patients During Tooth Extraction

Sana  Somair; Shafi Ullah  Khan; Adnan  Babar; Syed Junaid  Hussain Bukhari; Shahrukh  Zafar; Ruhma  Tariq

doi:10.51253/pafmj.v76iSUPPL-1.12944

Authors

Sana Somair Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Shafi Ullah Khan Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Adnan Babar Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Syed Junaid Hussain Bukhari Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Shahrukh Zafar Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Ruhma Tariq Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-1.12944

Keywords:

Anesthesia, Blood Pressure, Epinephrine, Hypertension, Normotension

Abstract

Objective: To examine the effect of injecting Epinephrine containing local anesthetic on the blood pressure and pulse rate of hypertensive patients in comparison to normotensive patients.

Study Design: Quasi-experimental study.

Place and Duration of Study: Tertiary care dental hospital, Rawalpindi, Pakistan, from May to Oct 2024.

Methodology: A total of 92 participants were sampled through consecutive purposive sampling technique. The patients distributed into Group-A were Hypertensive (blood pressure ≥140/90 mmHg), and in Group-B (control group) were Normotensive (with blood pressure ranging from <120-139/80-89 mmHg). The changes in blood pressure and pulse rate were evaluated at baseline, 2 minutes after anesthesia administration, 5 minutes after anesthesia administration, and after tooth extraction. SPSS was used for statistically analyzing the differences in blood pressure and pulse rate changes in both groups.

Results: Significant differences were observed between all-time points in both groups for pulse rate and blood pressure, systolic and diastolic (p < 0.001). However, the overall mean change in systolic blood pressure between the two groups (4.29 ± 0.67 in Group-A and 4.68 ± 1.22 in Group-B) did not differ statistically significantly (p = 0.065). Additionally, there was no significant difference in the mean pulse rate between the two groups overall (p = 0.921).

Conclusion: The Epinephrine-anesthetics with a dose of 2% Lignocaine with 1:100,000 Epinephrine (0.036mg) are generally safe for administering during dental procedures in hypertensive patients.

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