Saphenous Vein Graft vs. Radial Artery Graft: Searching for the Best Second Conduit in Coronary Artery Bypass Grafting

Authors

  • Imtiaz Ahmed Chaudhry Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi, Pakistan
  • Naser Ali Khan Department of Adult Cardiac Surgery, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi, Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-3.13033

Keywords:

Complication, Conduit, In-hospital outcome, Radial artery, Graft patency.

Abstract

Objective: To compare early in hospital outcomes between Radial Artery (RA) graft and saphenous vein grafts (SVG) in patients undergoing Coronary Artery Bypass Graft (CABG) surgery.

Study Design: Quasi Experimental study.

Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi Pakistan, from Oct 2021-Nov 2024.

Methodology: Three hundred and ninety-one patients with over age of 18 years, regardless of gender who underwent isolated On-pump CABG were recruited through non probability consecutive sampling. Patients were non-randomly allocated into two groups; Group-A (LIMA+VG) and Group-B (LIMA+RA+VG). Data on demographic, preoperative, intraoperative, and postoperative characteristics was collected using a structured proforma from adult cardiac surgery database. In-hospital outcomes and post-operative complications were compared between the study groups.

Results: Out of 391 patients, 76(19.4%) were females and 315(80.6%) were males with median age of 59.00(52.00-65.01) years. Group-A and Group-B had 182(46.5%) and 209(53.5%) patients respectively. Group-A had longer ICU stay duration compared to Group-B [45.50(22.00-91.00) vs. 29.00(21.00-61.00) hours; p<0.01]. In patients receiving three grafts, Group-A showed significantly higher chest tube drainage than Group-B [550.00(380.00-990.00ml) vs. 400.00(250.00-650.00ml); p=0.013]. The OR for type of graft was 2.03 (95% CI: 0.98-4.19; p=0.05), manifesting the borderline but significant impact on the postoperative complications.

Conclusion: RA grafts showed potential advantages over SVG as the second conduit in CABG surgery, especially in improving early in-hospital outcomes. Our findings emphasize the potential of RA graft use and support its frequent adoption in clinical practice particularly in younger population.

Downloads

Download data is not yet available.

References

Le NK, Mallick S, Chervu N, Butterfield J, Joachim K, Charland N, et al. Clinical and financial outcomes associated with the utilization of right internal mammary artery versus radial artery in multivessel coronary artery bypass grafting. Surgery 2024 https://doi.org/10.1016/j.surg.2024.04.011

Abromaitiene V, Greisen J, Kimose HH, Karaliunaite Z, Jakobsen CJ. Comparison of free arterial and saphenous vein grafting in outcomes after coronary bypass surgery. Scand. Cardiovasc. J 2022; 56(1): 42-47.

https://doi.org/10.1080/14017431.2022.2060525

Moya-Mendez ME, DeLaura I, Thornton SW, Williams AR, Zwischenberger BA. Quality improvement initiative to increase radial artery usage as a second arterial conduit in coronary artery bypass grafting. Ann Thorac Cardiovasc Surg 2024 ;38(5): ivae068. https://doi.org/10.1093/icvts/ivae068

Gharibeh L, Ferrari G, Ouimet M, Grau JB. Conduits' biology regulates the outcomes of coronary artery bypass grafting. Basic to Translational Science 2021; 6(4): 388-396.

https://doi.org/10.1016/j.jacbts.2020.11.015

Martins RS, Masood L, Kazi M, Gillani M, Sadiq A, Inam H, Fatimi S et al. Radial artery coronary bypass grafting: Surgical outcomes of an unexplored innovation in a developing country. J Pak Med Assoc 2022; 72(2): S106.

https://doi.org/10.47391/JPMA.AKU-22

Schwann TA, Tatoulis J, Puskas J, Bonnell M, Taggart D, Kurlansky P, et al., Worldwide trends in multi-arterial coronary artery bypass grafting surgery 2004-2014: a tale of 2 continents. J Thorac Cardiovasc Surg 2017; 29(3): 273-280.

https://doi.org/10.1053/j.semtcvs.2017.05.018

Yunus A, Banna HU, Naveed T. Early Results of Radial Artery as A Second Conduit in Coronary Artery Bypass Grafting in a Developing Country. Pak.J. Med. Health sci 2013; 17: 19-27

Momin A, Ranjan R, Valencia O, Jacques A, Lim P, Fluck D, et al Long Term Survival Benefits of Different Conduits Used in Coronary Artery Bypass Graft Surgery-A Single Institutional Practice Over 20 Years. J. Multidiscip. Health 2024 :1505-1512. https://doi.org/10.2147/JMDH.S461567

Tinica G, Chistol RO, Enache M, Leon Constantin MM, Ciocoiu M, et al. Long-term graft patency after coronary artery bypass grafting: Effects of morphological and pathophysiological factors. Anatol. J. Cardiol 2018; 20(5).

https://doi.org/10.14744/AnatolJCardiol.2018.51447

Dimagli A, Soletti Jr G, Harik L, Perezgrovas Olaria R, Cancelli G, et al Angiographic outcomes for arterial and venous conduits used in CABG. J. Clin. Med 2023; 12(5): 2022.

https://doi.org/10.3390/jcm12052022

Hamilton GW, Raman J, Moten S, Matalanis G, Rosalion A, Dimagli A, et al. Radial artery vs. internal thoracic artery or saphenous vein grafts: 15-year results of the RAPCO trials. Eur Heart J 2023; 44(26): 2406-2408.

https://doi.org/10.1093/eurheartj/ehad108

Tatoulis J, Schwann TA. Long term outcomes of radial artery grafting in patients undergoing coronary artery bypass surgery. Ann. Cardiothorac. Surg 2018; 7(5): 636.

https://doi.org/10.21037/acs.2018.05.11

Gaudino M, Benedetto U, Fremes S, Biondi-Zoccai G, Sedrakyan A, Puskas JD, A et al. Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery. NEJM 2018; 378(22): 2069-2070.

https://doi.org/10.1056/NEJMoa1716026

Jawitz OK, Cox ML, Ranney D, Williams JB, Mulder H, Gaudino MF, et al.. Outcomes following revascularization with radial artery bypass grafts: Insights from the PREVENT-IV trial. Am Heart J 2020; 228: 91-97.

https://doi.org/10.1016/j.ahj.2020.08.001

Achouh P, Isselmou KO, Boutekadjirt R, D'Alessandro C, Pagny JY, Fouquet R et al.. Reappraisal of a 20-year experience with the radial artery as a conduit for coronary bypass grafting. Eur J Cardio thorac Surg 2012; 41(1): 87-92.

https://doi.org/10.1016/j.ejcts.2011.05.027

Overgaard CB, Dzavík V. Inotropes and vasopressors: review of physiology and clinical use in cardiovascular disease. Circ 2008; 118(10): 1047-1056.

https://doi.org/10.1161/CIRCULATIONAHA.107.728840

Jasarevic M, Krueger O, Strathmann J, Jasarevic M, Shehada SE, Piotrowski JA, et al. Multiple Arterial Grafting During Coronary Artery Bypass Graft Surgery in Diabetic and Non-Diabetic Patients: A Short-and Long-Term Analysis at a Single Center J Clin Med 2024; 13(23): 7082.

https://doi.org/10.3390/jcm13237082

Tatoulis J. The radial artery: An important component of multiarterial coronary surgery and considerations for its optimal harvest. JTCVS techniques 2021; 5: 46-55.

https://doi.org/10.1016/j.xjtc.2020.10.042

He GW, Liu ZG. Comparison of nitric oxide release and endothelium-derived hyperpolarizing factor-mediated hyperpolarization between human radial and internal mammary arteries. Circ 2001; 104: I-344.

https://doi.org/10.1161/hc37t1.094930

Schwann TA, Al-Shaar L, Engoren M, Habib RH. Late effects of radial artery vs saphenous vein grafting for multivessel coronary bypass surgery in diabetics: a propensity-matched analysis. Eur J Cardio thorac Surg 2013; 44(4): 701-710.

https://doi.org/10.1093/ejcts/ezt061

Cohen G, Tamariz MG, Sever JY, Liaghati N, Guru V, Christakis GT, et al. The radial artery versus the saphenous vein graft in contemporary CABG: a case-matched study. Ann Thorac Surg. 2001; 71(1): 180-186.

https://doi.org/10.1016/S0003-4975(00)02285-2

Downloads

Published

30-05-2025

Issue

Section

Original Articles

Categories

How to Cite

1.
Ahmed Chaudhry I, Khan NA. Saphenous Vein Graft vs. Radial Artery Graft: Searching for the Best Second Conduit in Coronary Artery Bypass Grafting. Pak Armed Forces Med J [Internet]. 2025 May 30 [cited 2025 Aug. 23];75(SUPPL-3):S426-S433. Available from: https://www.pafmj.org/PAFMJ/article/view/13033