Efficacy of Corticosteroid versus Platelet-Rich Plasma in Patients presenting with Lateral Epicondylitis at A Tertiary Care Hospital
DOI:
https://doi.org/10.51253/pafmj.v76i6.13083Keywords:
Corticosteroid Injection, Dynamometer, Grip Strength, Lateral Epicondylitis, Platelet Rich Plasma, Tennis ElbowAbstract
Objective: To compare the efficacy of Platelet rich plasma (PRP) and corticosteroid injection in patient with Lateral Epicondylitis.
Study Design: Quasi-experimental study.
Place and Duration of Study: Department of Physical Medicine and Rehabilitation, Armed Force Institute of Rehabilitation Medicine Rawalpindi, Pakistan from Sep 2020 to Feb 2021.
Methodology: A total of 144 patients were included in the study. Patients chose between either Platelet Rich Plasma (PRP) treatment or corticosteroid intra-lesional injection. The latter were included in group-A, while the former was allocated to Group-B. Baseline and follow-up evaluations at one, two, and three months, numerical rating scale (NRS), patients rated tennis elbow evaluation (PRTEE), and grip strength using JAMAR® Dynamometer) were documented. Chi-square test was used to analyze data.
Results: This study enrolled 144 participants. Baseline PRTEE, NRS, and grip strength were comparable for both groups. At one and two months, Group-A showed better short-term improvement. At three months, however, Group-B demonstrated better PRTEE findings (p=0.009) and reduced NRS pain levels (p<0.001). Both groups saw a progressive increase in grip strength with no discernible differences. The study showed that PRP is better in terms of improvement in different parameters like PRTEE, NRS and grip strength in the longer-term.
Conclusion: This study showed there is no statistical significant difference in efficacy of platelet rich plasma and corticosteroids, with 100% efficacy seen in both groups with relatively better scores in PRP group as the follow-up duration increased.
Downloads
References
1. Bretschneider SF, Los FS, Eygendaal D, Kuijer PP, van der Molen HF. Work‐relatedness of lateral epicondylitis: Systematic review including meta‐analysis and GRADE work‐relatedness of lateral epicondylitis. Am J Ind Med 2022; 65(1): 41-50.
https://doi.org/10.1002/ajim.23303
2. Morya VK, Shahid H, Lang J, Kwak MK, Park SH, Noh KC. Advancements in Therapeutic Approaches for Degenerative Tendinopathy: Evaluating Efficacy and Challenges. Int J Mol Sci 2024; 25(21): 11846.
https://doi.org/10.3390/ijms252111846
3. Lu J, Li H, Zhang Z, Xu R, Wang J, Jin H. Platelet-rich plasma in the pathologic processes of tendinopathy: a review of basic science studies. Front Bioeng Biotechnol 2023; 11: 1187974.
https://doi.org/10.3389/fbioe.2023.1187974
4. Stegink-Jansen CW, Bynum JG, Lambropoulos AL, Patterson RM, Cowan AC. Lateral epicondylosis: a literature review to link pathology and tendon function to tissue-level treatment and ergonomic interventions. J Hand Therap 2021; 34(2): 263-297.
https://doi.org/10.1016/j.jht.2021.05.005
5. Park HB, Gwark JY, Im JH, Na JB. Factors associated with lateral epicondylitis of the elbow. Orthop J Sports Med 2021; 9(5): 23259671211007734. https://doi.org/10.1177/23259671211007734
6. Di Filippo L, Vincenzi S, Pennella D, Maselli F. Treatment, diagnostic criteria and variability of terminology for lateral elbow pain: findings from an overview of systematic reviews. Healthcare 2022; 10(6): 1095. https://doi.org/10.3390/healthcare10061095
7. Akbar H, Akbar S, Saddique MN, Sarfraz MS. Prevalence of lateral epicondylitis among housewives in Lahore: a cross-sectional study. BMC Musculoskelet Disord 2024; 25(1): 815.
https://doi.org/10.1186/s12891-024-07889-x
8. Kinney WR, Anderson BR. Nonoperative management of lateral epicondyle tendinopathy: an umbrella review. J Chiropr Med ;22(3): 204-211. https://doi.org/10.1016/j.jcm.2023.04.004
9. Kıvrak A, Ulusoy I. Comparison of the clinical results of platelet-rich plasma, steroid and autologous blood injections in the treatment of chronic lateral epicondylitis. Healthcare 2023; 11(5): 767. https://doi.org/10.3390/healthcare11050767
10. Niedermeier SR, Crouser N, Speeckaert A, Goyal KS. A survey of fellowship-trained upper extremity surgeons on treatment of lateral epicondylitis. Hand 2019; 14(5): 597-601.
https://doi.org/10.1177/1558944718770212
11. Arirachakaran A, Sukthuayat A, Sisayanarane T, Laoratanavoraphong S, Kanchanatawan W, Kongtharvonskul J. Platelet-rich plasma versus autologous blood versus steroid injection in lateral epicondylitis: systematic review and network meta-analysis. J Orthop Traumatol 2016; 17(1): 101-112.
https://doi.org/10.1007/s10195-015-0376-5
12. Shiri R, Viikari-Juntura E, Varonen H, Heliövaara M. Prevalence and determinants of lateral and medial epicondylitis: a population study. Am J Epidemiol 2006; 164(11): 1065-1074.
https://doi.org/10.1093/aje/kwj325
13. Wong JR, Toth E, Rajesparan K, Rashid A. The use of platelet-rich plasma therapy in treating tennis elbow: A critical review of randomised control trials. J Clin Orthop Trauma 2022; 32: 101965. https://doi.org/10.1016/j.jcot.2022.101965
14. Jacobson JA, Yablon CM, Henning PT, Kazmers IS, Urquhart A, Hallstrom B, et al. Greater trochanteric pain syndrome: percutaneous tendon fenestration versus platelet‐rich plasma injection for treatment of gluteal Tendinosis. J Ultrasound Med 2016; 35(11): 2413-2420.
https://doi.org/10.7863/ultra.15.11046
15. Lin MT, Chiang CF, Wu CH, Huang YT, Tu YK, Wang TG. Comparative effectiveness of injection therapies in rotator cuff tendinopathy: a systematic review, pairwise and network meta-analysis of randomized controlled trials. Arch Phys Med Rehabil 2019; 100(2): 336-349.
https://doi.org/10.1016/j.apmr.2018.06.028
16. Li A, Wang H, Yu Z, Zhang G, Feng S, Liu L. Platelet-rich plasma vs corticosteroids for elbow epicondylitis: a systematic review and meta-analysis. Med 2019; 98(51): e18358.
http://dx.doi.org/10.1097/MD.0000000000018358
17. Lebiedziński R, Synder M, Buchcic P, Polguj M, Grzegorzewski A, Sibiński M. A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis. Int Orthop 2015; 39: 2199-2203.
https://doi.org/10.1007/s00264-015-2861-0
18. Gosens T, Peerbooms JC, van Laar W, denOudsten BL. Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up. Am J Sports Med 2011; 39(6): 1200-1208.
https://doi.org/10.1177/0363546510397173
19. Oudelaar BW, Peerbooms JC, Huis VR, Vochteloo AJ. Concentrations of blood components in commercial platelet-rich plasma separation systems: a review of the literature. Am J Sports Med 2019; 47(2): 479-487.
Downloads
Published
License
Copyright (c) 2026 Omar Shafiq, Noreen Akhtar, Samra Iram, Umer Younas, Tameem Ul Hassan, Imran Irshad

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.





