Comparative Evaluation of Macro Minerals Status in Serum  of Diabetes Mellitus Patients and Healthy Individuals

Muhammad Ahmad; Farzana Hakim; Rabia Parveen; Sana; Ayesha Rafiq; Muhammad Iqbal

doi:10.51253/pafmj.v76iSUPPL-5.13313

Authors

Muhammad Ahmad Department of General Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Farzana Hakim Department of Biochemistry, Foundation University Rawalpindi Pakistan
Rabia Parveen Department of General Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Sana Department of Nutrition, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Ayesha Rafiq Department of General Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Muhammad Iqbal Department of General Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-5.13313

Keywords:

Calcium, Diabetes mellitus, glycosylated hemoglobin, hypoglycemics, Magnesium, Potassium, Phosphate, Sodium, Vitamin B12, Vitamin D, Zinc

Abstract

Objective: To compare Vitamin B12, Vitamin D, Zinc, Calcium, Sodium, Potassium, Folate, Magnesium and Phosphate levels in Diabetes mellitus patients on oral hypoglycemics (OHG) with healthy population

Study Design: Comparative cross sectional study

Place and Duration of Study: Outdoor Patient Department, Pak Emirates Military Hospital Rawalpindi, Pakistan from Jan to Dec 2024

Methodology: Patients were selected into Group-1 (diabetic) and Group-2 (non-diabetic) according to inclusion and exclusion criteria using non-probability consecutive sampling method. A questionnaire drafted to collect additional information from patients about demographics and treatment being taken was used. Blood samples were collected on spot for Vitamin B12, Vitamin D, Zinc, Calcium, Sodium, Potassium, Folate, Magnesium, Phosphate and HbA1C levels. WHO classification of Diabetes mellitus was taken as case definition of Diabetes mellitus for Group-1 while persons who did not have the Diabetes mellitus (type-2) were enrolled as non-diabetic cases for Group-2. Comparison of the vitamin and mineral parameters between two groups was done using independent sample t-test and Mann Whitney U test for respective sample types at a p-value of <0.05 as significant.

Result: p values of Vitamin B12 and Zinc were significant between Group-1 and Group-2 while insignificant for other minerals and vitamins studied.

Conclusion: Patients with Diabetes mellitus on treatment have significantly low Vitamin B12 and Zinc values in comparison to healthy population

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