Comparison of Pulmonary Vascular Resistance Measurements by Echocardiography and Cardiac Catheterization
DOI:
https://doi.org/10.51253/pafmj.v75iSUPPL-7.13464Keywords:
Cardiac catheterization, Echocardiography, Pulmonary hypertension, Pulmonary vascular resistanceAbstract
Objective: To compare Pulmonary Vascular Resistance (PVR) measurements by echocardiography and cardiac catheterization.
Study Design: Analytical cross-sectional study
Place and Duration of Study: Department of Paediatric Cardiology, Armed Forces Institute of Cardiology & National Institute of Heart Diseases, Rawalpindi Pakistan from Jun to Nov 2024.
Methodology: Consecutive sampling was used to recruit thirty-one patients. Included patients were between the ages of 2 and 60, who were having cardiac catheterization for suspected pulmonary vascular disease or PH. A detailed echocardiographic assessment was performed within 24 hours, including tricuspid regurgitation velocity (TRV) and the velocity-time integral of the right ventricular outflow tract (VTIRVOT). These characteristics were then compared to PVR measurements obtained using catheterization.
Results: Out of 31 cases, 16(51.6%) were males and 15(48.38%) were females with median age of 6.90(22.00-3.00) years. A moderate positive correlation was observed between PVR measured by echocardiography and cardiac catheterization in Wood units (WU) (r=0.41; p=0.02). This r-value reflects moderate consistency between non-invasive and invasive measurements of PVR. Bland- Strong agreement between the PVR measured by catheterization and echocardiography was demonstrated by Altman analysis. The 78.6% sensitivity and 82.4% specificity were observed for a PVR of >2 WU with a TRV/VTIRVOT threshold of 0.179 (AUC: 0.752, 95% CI: 0.55 to 0.94; p=0.001).
Conclusion: Echocardiography can provide a simple, reliable, noninvasive and potentially cost-effective alternative to determine PVR. The strong correlation and agreement between echocardiography-derived and catheterization-based PVR measurements show its potential as a valuable diagnostic tool, reducing the need for invasive testing.
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