Association of Polycystic Ovarian Syndrome with Mental Stress in Women of Reproductive   Age Group

Authors

  • Amina Zulfiqar Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan
  • Malahat Mansoor Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan
  • Munawar Afzal Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan
  • Faraz Bakht Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan
  • Marriam Sarfraz Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan
  • Sajida Karamat Department of Obstetrics & Gynecology, Sughra Shafi Medical Complex, Narowal Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-1.13739

Keywords:

Perceived Stress Score, Polycystic Ovarian Syndrome, Reproductive Age Group, Stress

Abstract

Objective: To determine the association of polycystic ovarian syndrome with stress in women of reproductive age group.

Study Design: Case control study.

Place and Duration of Study: Department of Obstetrics & Gynecology, Sughra Shafi Hospital, Narowal Pakistan, from Feb to Jul 2025.

Methodology: Five hundred and thirty women were included in the study from OPD and were divided in two groups i.e. cases were those who were diagnosed with PCOS and controls were those who did not have PCOS. Then women were examined for perceived stress score and if score If >13, then stress was labeled.

Results: In this study, the mean age of women in case group was 30.30±8.57 years and in control group was 31.26±8.80 years. The stress was observed in 175(66.0%) women in case group while in 82(30.9%) women in control groups with the OR =4.339 (95% CI: 3.016, 6.245).

Conclusion: There is significant association of stress with PCOS among women of reproductive age group.

Downloads

Download data is not yet available.

References

1. Basu BR, Chowdhury O, Saha SK. Possible link between stress-related factors and altered body composition in women with polycystic ovarian syndrome. J Human Reprod Sci 2018; 11(1): 10-8. http://doi.org/.4103/jhrs.JHRS_78_17

2. Parker J, O’brien C, Hawrelak J, Gersh FL. Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment. Int J Environ Res Public Health 2022; 19(3): 1336.

http://doi.org/10.3390/ijerph19031336

3. Chaudhari AP, Mazumdar K, Mehta PD. Anxiety, depression, and quality of life in women with polycystic ovarian syndrome. Indian J Psychol Med 2018; 40(3): 239-246.

http://doi.org/10.4103/IJPSYM.IJPSYM_561_17

4. Thannickal A, Brutocao C, Alsawas M, Morrow A, Zaiem F, Murad MH, et al. Eating, sleeping and sexual function disorders in women with polycystic ovary syndrome (PCOS): A systematic review and meta‐analysis. Clin Endocrinol 2020; 92(4): 338-349. http://doi.org/10.1111/cen.14153

5. Sadeeqa S, Mustafa T, Latif S. Polycystic ovarian syndrome–related depression in adolescent girls: a review. J Pharm Bioallied Sci 2018; 10(2): 55-59.

http://doi.org/10.4103/JPBS.JPBS_1_18

6. Kolhe JV, Chhipa AS, Butani S, Chavda V, Patel SS. PCOS and depression: common links and potential targets. Reprod Sci 2022; 29: 3106–3123. https://doi.org/10.1007/s43032-021-00765-2

7. Alamri AS, Alhomrani M, Alsanie WF, Almuqbil M, Alqarni KM, Alshehri SM, et al. Role of polycystic ovarian syndrome in developing psychological burden in Saudi Arabian females: A case control study. Front Public Health 2022; 10(1): 999813.

https://doi.org/10.3389/fpubh.2022

8. Lin H, Liu M, Zhong D, Ng EHY, Liu J, Li J, et al. The prevalence and factors associated with anxiety-like and depression-like behaviors in women with polycystic ovary syndrome. Front Psychiatry 2021; 12: 709674.

http://doi.org/10.3389/fpsyt.2021

9. Dybciak P, Humeniuk E, Raczkiewicz D, Krakowiak J, Wdowiak A, Bojar I. Anxiety and Depression in Women with Polycystic Ovary Syndrome. Medicina 2022; 58(7): 942.

https://doi.org/10.3390/medicina58070942

10. Kite C, Atkinson L, McGregor G, Clark CCT, Brown JE, Kyrou I, et al. Sleep Disruption and Depression, Stress and Anxiety Levels in Women With Polycystic Ovary Syndrome (PCOS) During the Lockdown Measures for COVID-19 in the UK. Front Glob Women Health 2021; 2: 649104.

https://doi.org/10.3389/fgwh.2021

11. Damone AL, Joham AE, Loxton D, Earnest A, Teede HJ, Moran LJ. Depression, anxiety and perceived stress in women with and without PCOS: a community-based study. Psychol Med 2019; 49(9): 1510-1520.

http://doi.org/10.017/S0033291718002076

12. Salari N, Babajani F, Hosseinian-Far A, Hasheminezhad R, Abdoli N, Haydarisharaf P, et al. Global prevalence of major depressive disorder, generalized anxiety, stress, and depression among infertile women: a systematic review and meta-analysis. Arch Gynecol Obstet 2024; 309(5): 1833-1846.

https://doi.org/10.007/s00404-024-7444-y

13. Basu BR, Chowdhury O, Saha SK. Possible Link Between Stress-related Factors and Altered Body Composition in Women with Polycystic Ovarian Syndrome. J Human Rep Sci 2018; 11(1): 10-18. http://doi.org/.4103/jhrs.JHRS_78_17

14. Benjamin JJ, MaheshKumar K, Radha V, Rajamani K, Puttaswamy N, Koshy T, et al. Stress and polycystic ovarian syndrome-a case control study among Indian women. Clin Epidemiol Glob Health 2023; 22: 101326.

https://doi.org/10.1016/j.cegh.2023

15. Altaf K, Mehreen K, Khatoon B, Tariq M. Role of Stress in Onset of Polycystic Ovarian Syndrome (PCOS). J Health Rehab Res 2023; 3(2): 1122-1127.

https://doi.org/10.61919/jhrr.v3i2.276

16. Divya M, Ranganathan S. "PCOS is Like having a Disease": The Everyday Stress of Living with Polycystic Ovarian Syndrome (PCOS). Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine 2022; 47(4): 622-623.

http://doi.org/10.4103/ijcm.ijcm_1374_21

17. Khafagy G, El Sayed I, Abbas S, Soliman S. Perceived Stress Scale Among Adolescents with Polycystic Ovary Syndrome. Int J Women Health 2020; 12: 1253-1258.

http://doi.org/10.2147/ijwh.s279245

18. Tabassum F, Jyoti C, Sinha HH, Dhar K, Akhtar MS. Impact of polycystic ovary syndrome on quality of life of women in correlation to age, basal metabolic index, education and marriage. PloS One 2021; 16(3): e0247486.

https://doi.org/10.1371/journal.pone

19. Benjamin JJ, Kuppusamy M, Koshy T, Kalburgi Narayana M, Ramaswamy P. Cortisol and polycystic ovarian syndrome - a systematic search and meta-analysis of case-control studies. Gynecol Endocrinol 2021; 37(11): 961-967.

https://doi.org/10.1080/09513590.2021.1908254

20. Marschalek M-L, Marculescu R, Schneeberger C, Marschalek J, Dewailly D, Ott J. A case-control study about markers of stress in normal-/overweight women with polycystic ovary syndrome and in controls. Front Endocrinol 2023; 14(1): 1173422.

https://doi.org/10.3389/fendo.2023

21. Aversa A, La Vignera S, Rago R, Gambineri A, Nappi RE, Calogero AE, et al. Fundamental Concepts and Novel Aspects of Polycystic Ovarian Syndrome: Expert Consensus Resolutions. Front Endocrinol 2020; 11(1): 516.

https://doi.org/10.3389/fendo.2020.00516

22. Yin X, Ji Y, Chan CLW, Chan CHY. The mental health of women with polycystic ovary syndrome: a systematic review and meta-analysis. Arch Women Mental Health 2021; 24(1): 11-27. https://doi.org/10.1007/s00737-020-1043-x

Downloads

Published

30-01-2026

Issue

Section

Original Articles

Categories

How to Cite

1.
Amina Zulfiqar, Malahat Mansoor, Munawar Afzal, Faraz Bakht, Marriam Sarfraz, Sajida Karamat. Association of Polycystic Ovarian Syndrome with Mental Stress in Women of Reproductive   Age Group. Pak Armed Forces Med J [Internet]. 2026 Jan. 30 [cited 2026 Feb. 6];76(SUPPL-1):S287-S291. Available from: https://www.pafmj.org/PAFMJ/article/view/13739