EFFECT OF PREOPERATIVE STEROIDS ON PERIOPERATIVE AND POSTOPERATIVE HAEMORRHAGE IN PATIENTS UNRERGOING FESS

Effect of Preoperative Steroids

Abstract

Objective: To compare the effect of preoperative oral steroids (prednisolone) on perioperative and postoperative hemorrhage in patients undergoing functional endoscopic sinus surgery for chronic sinusitis with those who do not receive steroids.
Design: Randomized controlled trials.
Place and duration of study: This study was conducted in ENT Department Shaikh Khalifa Bin Zayed Al Nahyan Hospital (CMH) Muzaffarabad from 15th Jan 2010 to 20th Feb 2011.
Patients and Methods: After getting informed consent total of 60 patients who fulfilled the inclusion criteria were selected and functional endoscopic sinus surgery was carried out. They were divided into two groups of 30 each by using random number tables. Group A received prednisolone in a dose of 01 mg/kg body weight for 01 week prior to surgery (last day of dose being the day prior to operative day) while group B (control group) did not receive any steroid.
Results: There was a significant difference in both perioperative and postoperative hemorrhage with better control rates in group A.
Conclusion: Prednisolone given preoperatively significantly reduces the morbidity that is perioperative and postoperative hemorrhage thus early recovery to normal life style in patients undergoing functional endoscopic sinus surgery for chronic sinusitis.