INVASIVE MOLE AT 22 WEEK GESTATION WITH PERFORATION OF UTERUS

Invasive Mole

Abstract

The Gestational trophoblastic diseases (GTD) are a group of pregnancy related disorders arising from abnormal placental trophoblastic cells. It comprises two premalignant conditions: partial and complete hydatidiform mole and, Malignant Gestational Trophoblastic Neoplasia (GTN). Histologically GTNs are classified into 3 subgroups: choriocarcinoma destruens (invasive mole, IM), choriocarcinoma (CC) and a rare placental site trophoblastic tumour (PSTT)1.
IM is characterized by trophoblastic proliferation invading the myometrium with edematous chorionic villi5. These trophoblastic villi differentiate IM from CC.