Haematological Parameters in Patients of Covid-19 from Baltistan
DOI:
https://doi.org/10.51253/pafmj.v76iSUPPL-5.6233Keywords:
Absolute Neutrophil Count, COVID-19, C-Reactive Protein, Neutrophil to Lymphocyte Ratio, Polymerase Chain Reaction.Abstract
Objective: To determine hematological parameters and C-reactive protein (CRP) in patients of Corona virus disease 2019 (COVID-19) from Baltistan.
Study Design: Cross-sectional study.
Place and Duration of Study: Combined Military Hospital, Skardu Pakistan, from Jul to Sep 2020.
Methodology: One hundred and ninety-four patients presenting with signs and symptoms suggestive of COVID-19 were included. They were divided into two equal groups on result of polymerase chain reaction (PCR) for severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). PCR positive patients were included in Group-A and PCR negative in Group-B. Blood samples of patients from both groups were tested for total leukocyte count (TLC), absolute neutrophil count (ANC), absolute lymphocyte count (ALC), neutrophil to lymphocyte ratio (NLR), haemoglobin (Hb), platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT), D-Dimer and CRP. Results of both groups were compared using appropriate statistical tests.
Results: Statistically significant difference was found between mean values of TLC, ANC, NLC and platelet count of both groups. Mean±SD value of TLC, ANC, NLR and platelet count of groups A and B were 6.91±2.26 x 109/l and 8.90±3.79 x 109/l, 4.71±2.20 x 109/l and 6.77±3.68 x 109/l, 3.99±4.38 and 5.73±5.46, 196.52±64.71 x 109/l and 229.09±132.43 x 109/l, respectively. The difference in mean values of ALC, Hb, PT, APTT, D-Dimer and CRP of both groups was not statistically significant.
Conclusion: In patients with symptoms suggestive of COVID-19, total leukocyte count, absolute neutrophil count, neutrophil to lymphocyte ratio and platelet count may help in diagnosis.
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