DIFFERENCE IN OUTCOMES IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION, TREATED WITH THROMBOLYSIS VERSUS PRIMARY PERCUTANEOUS CORONARY INTERVENTION

Abstract

Objective: To compare the outcomes in terms of MACE i.e. death, stroke, reinfarction and heart failurein patients with STelevation Myocardial infarction treated with intravenous thrombolysis versus primary percutaneous coronary intervention (PPCI).

Study Design: Comparative cross-sectional study.

Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi and Hayat Abad Medical Complex, Peshawar, from Oct 2019 to Apr 2020.

Methodology: In the current study a total of 204 (102 patients in each group) patients were observed. All the patients presenting with ST-elevation Myocardial infarction in age between 30-75 years and both genders were included.102 patients treated with thrombolysis and 102 patients with Primary PCI were included in the study. Both the groups were admitted as per standard protocol and were followed-up for 7 days, discharged patients before 7 days were contacted through contact number (two contact numbers of patient and close relative). The outcomes were noted.

Results: Our study shows that in group A (thrombolysis) mean age was 44 years with SD ± 9.91. Whereas in group B (PPCI) mean age was 46 years with SD ± 10.02. In group A 69(68%) patients were male and 33 (32%) patients were female. Whereas in group B 67(66%) patients were male and 35(34%) patients were female. In group A 18 (17.6%) patients had MACE. Whereas in group B 8 (7.8%) patients had MACE.

Conclusion: Our study concludes that the overall MACE rate in ST elevation Myocardial infarction was 13%. Moreover, the MACE rate was more in intravenous thrombolysis as compared to primary percutaneous coronary intervention in patients presenting with ST elevation Myocardial infraction.