Comparison of Pre-Operative Intravenous Versus Oral Glucose Administration on Recovery Outcome in Post-Anesthesia Care Unit in Colorectal Surgery Patients

Muhammad Huzaifa Sharif; Osama  Mateen; Syed Zeeshan  Haider; Taimur Azam  Khan; Safwan Ahmed  Tariq; Abrar Ahmed  Awan

doi:10.51253/pafmj.v75i3.9381

Authors

Muhammad Huzaifa Sharif Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Osama Mateen Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Syed Zeeshan Haider Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Taimur Azam Khan Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Safwan Ahmed Tariq Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Abrar Ahmed Awan Department of Anaesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i3.9381

Keywords:

Carbohydrate, Colorectal, Dextrose, Intravenous, Oral, recovery.

Abstract

Objective: To explore the recovery outcome after pre-operative administration of glucose (Carbohydrate/Dextrose) in the oral versus intravenous form in patients undergoing elective colorectal surgery in the post-anesthesia care unit.

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Anesthesiology, Combined Military Hospital Rawalpindi, Pakistan from Aug 2022-Jan 2023.

Methodology: A Quasi-experimental study was conducted in which 160 patients were divided into two groups of 80 patients each. After the fasting duration of 8 hours, Group-O received 1 g/kg of Dextrose dissolved in 100 ml of normal saline administered orally 2 hours prior to surgery whereas Group-I received 1g/kg of Dextrose dissolved in 100 ml of Normal Saline administered intravenously 2 hours prior to surgery. Variables measured were post-operative pain on Visual Analog Scale (VAS), incidence of nausea, vomiting, thirst, hunger, fatigue, and anxiety.

Results: Stay in recovery did not significantly change between both groups with 5.29±0.25 hours in the Intravenous group versus 5.28±0.27 hours in the Oral group (p 0.60). However, post-operative pain scales were significantly different with 3.28±0.57 versus 4.13±0.41 between both groups (p<0.0001).

Conclusion: The Intravenous glucose administration results in better post-operative pain scores with less incidence of nausea, vomiting and fatigue whereas the oral administration of glucose provides decrease incidence of thirst, hunger, and anxiety

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