Frequency of Hypoglycemia in Neonates with Intrauterine Growth Restriction Presenting to Pak-Emirates Military Hospital Neonatal Intensive Care Uni

Aqsa Zafar; Muhammad Tariq Nadeem; Tamoor Afzal; Hira Ahmed; Amina Pirzada; Maryam Waheed

doi:10.51253/pafmj.v75i3.10179

Authors

Aqsa Zafar Department of Pediatrics, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Muhammad Tariq Nadeem Department of Pediatrics, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Tamoor Afzal Department of Pediatric Surgery, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Hira Ahmed Department of Pediatrics, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Amina Pirzada Department of Pediatrics, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Maryam Waheed Department of Pediatrics, Combined Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i3.10179

Keywords:

Hypoglycaemia, Intrauterine Growth Restriction, Neonates.

Abstract

Objectives: To determine the frequency of hypoglycemia in neonates born with intra-uterine growth restriction.

Study Design: Cross-sectional study.

Place and Duration of Study: Department of Paediatrics, Pak-Emirates Military Hospital, Rawalpindi, Jan to Sep 2022.

Methodology: This study was conducted on 127 neonates diagnosed with intrauterine growth restriction. Neonates with IUGR who were born at term were included in the study. Those born to diabetic mothers, with chronic disorders, or were born with birth asphyxia or meconium aspiration were excluded. Neonates were tested for blood glucose levels at birth and then at hourly intervals for five hours post-birth.

Results: We studied a sample with a mean gestational age at birth of 38.56±1.48, of whom 72(56.7%) were female. The sample had the lowest mean blood glucose levels at three- and four hours after birth. A total of 52(40.9%) neonates developed hypoglycemia at least once during the five-hour observation period. Neonates who were delivered via cesarean section had a significantly lower frequency of development of hypoglycemia compared to those delivered per vaginum (p=0.012). Other factors such as neonatal gender, gestational age at birth, maternal history of smoke exposure, abortions or previous neonatal death, and antenatal care receipt were not associated with an increase in the frequency of hypoglycemia (p>0.05).

Conclusion: Hypoglycaemia is common in neonates suffering from intrauterine growth retardation and requires adequate monitoring in this population.

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