Comparison of Two Different Doses of Dexmedetomidine in Lumbar Transforaminal Block for Treatment of Lumbar Radicular Pain in Tertiary Care Hospital inRawalpindi

Komal Babur; Liaquat Ali; Khaleel Ahmed; Soman Iqbal; Malaika Nasir; Kalim Ullah

doi:10.51253/pafmj.v75i5.11058

Authors

Komal Babur Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan
Liaquat Ali Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan
Khaleel Ahmed Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan
Soman Iqbal Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan
Malaika Nasir Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan
Kalim Ullah Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i5.11058

Keywords:

Bradycardia, Dexmedetomidine, Oswestry Disability Index, Visual Analog Scale

Abstract

Objective: To compare two different doses of Dexmedetomidine in lumbar transforaminal block for treatment of lumbar radicular pain in tertiary care hospital in Rawalpindi.

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan, from Oct 2022 to Oct 2023.

Methodology: A total of 60 patients, aged 30 to 60 years, experiencing lumbar radicular pain due to disc protrusion were included in this study. They were randomly divided into two equal groups. Group-A received a dose of 0.2mcg/kg Dexmedetomidine, while Group-B received 0.5mcg/kg Dexmedetomidine. Data pertaining to post-operative parameters was collected using a standardized proforma and analyzed using SPSS.

Results: Sixty patients who received lumbar transforaminal blocks to relieve lumbar radicular pain were methodically divided into two groups of thirty people each. Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) revealed no significant differences between Group-A and Group-B (p>0.05). There is no significant difference in hypotension incidence between Group-A (6.7%) and Group-B (40.0%) at baseline for blood pressures of 100/60 and higher (p=0.765). However, Group-A demonstrated a significantly lower bradycardia incidence (26.7%) compared to Group-B (36.7%) for heart rates <65 bpm (p=0.003). Also, Group-A showed lower incidence of nausea (13.3%) compared to Group-B (30.0%), but the difference was not statistically significant (p=0.160).

Conclusion: The study showed that both groups showed no significant difference in pain intensity and disability index, however, 0.2mcg/kg Dexmedetomidine exhibited a lower incidence of bradycardia and nausea, indicating a potential safety advantage over 0.5mcg/kg Dexmedetomidine. However,

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