COVID-19 Breakthrough Cases: A Descriptive Study from Pakistan Naval Hospitals

Chaudhry Muhammad Qamar Ul Haq Noor; Wasim Alamgir; Gulnaz Ahmad; Muhammad Aslam Channa; Muhammad Usman Rafique; Afaq Ahmed

doi:10.51253/pafmj.v75iSUPPL-5.7533

Authors

Chaudhry Muhammad Qamar Ul Haq Noor Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
Wasim Alamgir Department of Medicine, General Headquarters, Rawalpindi Pakistan
Gulnaz Ahmad Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
Muhammad Aslam Channa Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
Muhammad Usman Rafique Department of Accounting & Finance, Medical Directorate, Naval Headquarters, Islamabad Pakistan
Afaq Ahmed Department of Information Security, Medical Directorate, Naval Headquarters, Islamabad Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-5.7533

Keywords:

COVID-19, COVID-19 Breakthrough Infection, Cansino, Sinopharm, Sinovac, Sputnik.

Abstract

Objective: To measure the frequency of COVID-19 breakthrough infection in entitled vaccinated clientele of Pakistan Navy.
Study Design: Prospective longitudinal study
Place and Duration of Study: Naval Hospitals at Islamabad and Karachi Pakistan, from Mar to Aug 2021.
Methodology: Who received 04 types of vaccine including Sinopharm (n=18,246), Sinovac (n=10,716), Cansino (n=20,250) and
Sputnik vaccine (n=20,000). These individuals were monitored over time for development of COVID-19 infection. Vaccine
breakthrough case is defined as an individual who has SARS-CoV-2 RNA or antigen detected on a respiratory specimen
collected ≥14 days after completing the authorized SARS-CoV-2 vaccine. The data was collected by the record maintained in
hospital statistics office. The data was entered, stored and managed in the central data base as maintained at public health
department.
Results: Out of the total 69592 individuals who were inoculated 0.15% (i.e., n=111) cases developed COVID-19 breakthrough
infection. Cinopharm showed highest number of breakthrough cases 79(0.43%), Sinovac 19(0.17%), Cansino 07(0.034%) and
Sputnik 6(0.0003%). Age wise the highest recorded cases were belonging to less than 39 years followed by 37 cases among
individual aging 40 to 65 years, 08 cases in individuals age between 66 to 75 years and 10 cases were diagnosed in people
having more than 75 years of age.
Conclusion: Sinopharm vaccination was associated with highest frequency of breakthrough COVID-19 infection. While
Sputnik showed the least number of breakthrough COVID-19 infection cases.

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