COVID-19 Breakthrough Cases: A Descriptive Study from Pakistan Naval Hospitals

Authors

  • Chaudhry Muhammad Qamar Ul Haq Noor Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
  • Wasim Alamgir Department of Medicine, General Headquarters, Rawalpindi Pakistan
  • Gul Naz Ahmad Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
  • Muhammad Aslam Channa Department of Health Care Administration, Medical Directorate, Naval Headquarters, Islamabad Pakistan
  • Muhammad Usman Rafique Department of Accounting & Finance, Medical Directorate, Naval Headquarters, Islamabad Pakistan
  • Afaq Ahmed Department of Information Security, Medical Directorate, Naval Headquarters, Islamabad Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-5.7533

Keywords:

COVID-19, COVID-19 Breakthrough Infection, Cansino, Sinopharm, Sinovac, Sputnik.

Abstract

Objective: To measure the frequency of COVID-19 breakthrough infection in entitled vaccinated clientele of Pakistan Navy.
Study Design: Prospective longitudinal study
Place and Duration of Study: Naval Hospitals at Islamabad and Karachi Pakistan, from Mar to Aug 2021.
Methodology: Who received 04 types of vaccine including Sinopharm (n=18,246), Sinovac (n=10,716), Cansino (n=20,250) and 
Sputnik vaccine (n=20,000). These individuals were monitored over time for development of COVID-19 infection. Vaccine 
breakthrough case is defined as an individual who has SARS-CoV-2 RNA or antigen detected on a respiratory specimen 
collected ≥14 days after completing the authorized SARS-CoV-2 vaccine. The data was collected by the record maintained in 
hospital statistics office. The data was entered, stored and managed in the central data base as maintained at public health 
department.
Results: Out of the total 69592 individuals who were inoculated 0.15% (i.e., n=111) cases developed COVID-19 breakthrough 
infection. Cinopharm showed highest number of breakthrough cases 79(0.43%), Sinovac 19(0.17%), Cansino 07(0.034%) and 
Sputnik 6(0.0003%). Age wise the highest recorded cases were belonging to less than 39 years followed by 37 cases among 
individual aging 40 to 65 years, 08 cases in individuals age between 66 to 75 years and 10 cases were diagnosed in people 
having more than 75 years of age.
Conclusion: Sinopharm vaccination was associated with highest frequency of breakthrough COVID-19 infection. While 
Sputnik showed the least number of breakthrough COVID-19 infection cases.

 

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Published

31-07-2025

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Original Articles

How to Cite

1.
Noor CMQUH, Alamgir W, Ahmad GN, Channa MA, Rafique MU, Ahmed A. COVID-19 Breakthrough Cases: A Descriptive Study from Pakistan Naval Hospitals. Pak Armed Forces Med J [Internet]. 2025 Jul. 31 [cited 2025 Aug. 1];75(SUPPL-5):S679-S683. Available from: https://www.pafmj.org/PAFMJ/article/view/7533